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Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is an opioid used to treat moderate to severe pain.[4] Typically, long-term use is only recommended for pain due to cancer.[6] It may be used by mouth or by injection into a vein, muscle, or under the skin.[4] Effects generally begin within half an hour and last for up to five hours.